Identification of RVR, a novel orphan nuclear receptor that acts as a negative transcriptional regulator.
نویسندگان
چکیده
منابع مشابه
Identification of a nuclear orphan receptor (Ear2) as a negative regulator of renin gene transcription.
A potent transcriptional enhancer was previously identified upstream of the mouse renin gene. Within the enhancer is a TGACCT direct-repeat motif, required for enhancer activity, that is the consensus sequence recognized by members of the thyroid hormone subfamily of steroid hormone receptors. We previously reported that RAR/RXR bind to this sequence and mediate the induction of renin promoter ...
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1 Hormone Research Center, School of Biological Science and Technology, Chonnam National University, Gwangju 500-757, Republic of Korea; 2 Research Institute of Medical Sciences, Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju 501746, Republic of Korea; 3 Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 440-746, Repub...
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ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 1994
ISSN: 0888-8809,1944-9917
DOI: 10.1210/mend.8.9.7838156